Semaglutide
Semaglutide (Ozempic, Wegovy)
Long-acting GLP-1 receptor agonist. Appetite suppression, glycemic control, weight loss.
Typical vial sizes
Sample reconstitution
2 mg vial · 2 mL bac water · 1.325 mg dose
- Draw volume
- 1.325 mL
- Insulin units
- 133 units
- Concentration
- 1.00 mg/mL
- Doses per vial
- 1.5
Research notes
Standard titration: 0.25 → 0.5 → 1.0 → 1.7 → 2.4mg over 16+ weeks.
From the blog
- GLP-1 Drugs, Pregnancy, and Contraception: What the Labels and Evidence Say
Both drug classes carry consistent pregnancy language. The manufacturers' prescribing information states these medicines should not be used during pregnancy and should be discontinued when pregnancy is recognized. The stated rationale is twof
- GLP-1 Drugs in Adolescents: What the Pediatric Obesity Evidence Actually Shows
GLP-1 receptor agonists moved into adult obesity care first, but two of them now carry U.S. pediatric indications, and the trials behind those approvals are worth reading closely. This is a research log entry, not clinical guidance: the goal here is
- Semaglutide and Kidney Disease: What the FLOW Trial Actually Showed
Semaglutide entered public awareness as a glucose-lowering and weight-loss drug. The FLOW trial is the study that pushed it into a third arena entirely: kidney protection. For anyone keeping a research log on GLP-1 receptor agonists, FLOW is a landma
- GLP-1 Drugs, the Gallbladder, and Pancreatitis: Reading the Safety Signals
GLP-1 receptor agonists like semaglutide and the dual GIP/GLP-1 agonist tirzepatide carry a cluster of upper-abdominal safety signals that get mentioned together and are easy to conflate: gallbladder
- GLP-1 Weight Loss and Bone Density: An Underdiscussed Concern
Most conversations about GLP-1 receptor agonists like semaglutide focus on the numbers on the scale. A quieter question sits underneath that headline: what happens to your skeleton when you lose weight quickly? Bone is metabo
Further reading
Links open live searches on authoritative databases — verify dosing and safety against primary sources.
Research use only.
Information on this page is a reference log compiled from public sources and is not medical advice. Consult a licensed physician before making any decisions about your health.